Survivin (BIRC5)

Definition:

Survivin (BIRC5) is known as a dual cellular functions protein that directly regulates both apoptosis and mitosis in embryonic cells during embryogenesis and in cancer cells during tumorigenesis and tumor metastasis.

References:

[1]. Lin TY, et al. BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells. Autophagy. 2020 Jul;16(7):1296-1313. [Content Brief]

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