Synaptotagmin-like protein 1

Definition:

May play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-trisphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity).

References:

[1]. Oliver Holt, et al. Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse. Traffic. 2008 Apr;9(4):446-57. [Content Brief]

[2]. J K McAdara Berkowitz, et al. JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase. J Biol Chem. 2001 Jun 1;276(22):18855-62. [Content Brief]

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