T-cell differentiation antigen CD6

[1]. Namir J Hassan, et al. Frontline: Optimal T cell activation requires the engagement of CD6 and CD166. Eur J Immunol. 2004 Apr;34(4):930-40. [Content Brief]

[2]. Cristina Escoda-Ferran, et al. Modulation of CD6 function through interaction with Galectin-1 and -3. FEBS Lett. 2014 Aug 25;588(17):2805-13. [Content Brief]

[3]. Idoia Gimferrer, et al. Relevance of CD6-mediated interactions in T cell activation and proliferation. J Immunol. 2004 Aug 15;173(4):2262-70. [Content Brief]

[4]. Aukje W Zimmerman, et al. Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells. Blood. 2006 Apr 15;107(8):3212-20. [Content Brief]

[5]. Namir J Hassan, et al. CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76. Mol Cell Biol. 2006 Sep;26(17):6727-38. [Content Brief]

[6]. Maria-Rosa Sarrias, et al. CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock. Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11724-9. [Content Brief]

[7]. Romain Roncagalli, et al. Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub. Nat Immunol. 2014 Apr;15(4):384-392. [Content Brief]