TNFAIP3-interacting protein 2
Definition:
References:
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[1]. Wei-Kuang Liu, et al. The inhibitor ABIN-2 disrupts the interaction of receptor-interacting protein with the kinase subunit IKKgamma to block activation of the transcription factor NF-kappaB and potentiate apoptosis. Biochem J. 2004 Mar 15;378(Pt 3):867-76. [Content Brief]
[2]. Laurent Leotoing, et al. A20-binding inhibitor of nuclear factor-kappaB (NF-kappaB)-2 (ABIN-2) is an activator of inhibitor of NF-kappaB (IkappaB) kinase alpha (IKKalpha)-mediated NF-kappaB transcriptional activity. J Biol Chem. 2011 Sep 16;286(37):32277-88. [Content Brief]
[3]. Wei-Kuang Liu, et al. An LKB1-interacting protein negatively regulates TNFalpha-induced NF-kappaB activation. J Biomed Sci. 2003 Mar-Apr;10(2):242-52. [Content Brief]
[4]. Amir Tadros, et al. ABIN-2 protects endothelial cells from death and has a role in the antiapoptotic effect of angiopoietin-1. Blood. 2003 Dec 15;102(13):4407-9. [Content Brief]
[5]. Chia-Yi Chien, et al. The A20-binding protein ABIN-2 exerts unexpected function in mediating transcriptional coactivation. FEBS Lett. 2003 May 22;543(1-3):55-60. [Content Brief]
[6]. V Lang, et al. ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability. Mol Cell Biol. 2004 Jun;24(12):5235-48. [Content Brief]