U6 snRNA phosphodiesterase 1
Definition:
References:
-
[1]. Vadim Shchepachev, et al. Human Mpn1 promotes post-transcriptional processing and stability of U6atac. FEBS Lett. 2015 Aug 19;589(18):2417-23. [Content Brief]
[2]. Yuichiro Nomura, et al. Structural and mechanistic basis for preferential deadenylation of U6 snRNA by Usb1. Nucleic Acids Res. 2018 Nov 30;46(21):11488-11501. [Content Brief]
[3]. Christine Hilcenko, et al. Aberrant 3' oligoadenylation of spliceosomal U6 small nuclear RNA in poikiloderma with neutropenia. Blood. 2013 Feb 7;121(6):1028-38. [Content Brief]
[4]. Allison L Didychuk, et al. Usb1 controls U6 snRNP assembly through evolutionarily divergent cyclic phosphodiesterase activities. Nat Commun. 2017 Sep 8;8(1):497. [Content Brief]
[5]. Yuichiro Nomura, et al. Structural basis for the evolution of cyclic phosphodiesterase activity in the U6 snRNA exoribonuclease Usb1. Nucleic Acids Res. 2020 Feb 20;48(3):1423-1434. [Content Brief]
[6]. Vadim Shchepachev, et al. Mpn1, mutated in poikiloderma with neutropenia protein 1, is a conserved 3'-to-5' RNA exonuclease processing U6 small nuclear RNA. Cell Rep. 2012 Oct 25;2(4):855-65. [Content Brief]
[7]. Seweryn Mroczek, et al. C16orf57, a gene mutated in poikiloderma with neutropenia, encodes a putative phosphodiesterase responsible for the U6 snRNA 3' end modification. Genes Dev. 2012 Sep 1;26(17):1911-25. [Content Brief]
Molarity Calculator
Dilution Calculator
