Ubiquitin carboxyl-terminal hydrolase 4
Definition:
References:
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[1]. Keiji Wada, et al. UnpEL/Usp4 is ubiquitinated by Ro52 and deubiquitinated by itself. Biochem Biophys Res Commun. 2006 Mar 31;342(1):253-8. [Content Brief]
[2]. Marcello Clerici, et al. The DUSP-Ubl domain of USP4 enhances its catalytic efficiency by promoting ubiquitin exchange. Nat Commun. 2014 Nov 18;5:5399. [Content Brief]
[3]. Keiji Wada, et al. Oncogenic protein UnpEL/Usp4 deubiquitinates Ro52 by its isopeptidase activity. Biochem Biophys Res Commun. 2006 Jan 20;339(3):731-6. [Content Brief]
[4]. Tetyana Milojevic, et al. The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2A receptor. Mol Pharmacol. 2006 Apr;69(4):1083-94. [Content Brief]
[5]. Iris Z Uras, et al. Ubiquitin-specific protease 4 inhibits mono-ubiquitination of the master growth factor signaling kinase PDK1. PLoS One. 2012;7(2):e31003. [Content Brief]
[6]. M Mehić, et al. The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function. Oncogenesis. 2017 Jun 12;6(6):e348. [Content Brief]
[7]. Eun Joo Song, et al. The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome. Genes Dev. 2010 Jul 1;24(13):1434-47. [Content Brief]