Zinc finger protein 768

Definition:

Binds to mammalian-wide interspersed repeat (MIRs) sequences in euchromatin and promoter regions of genes at the consensus sequence 5'-GCTGTGTG-[N20]-CCTCTCTG-3', consisting of two anchor regions connected by a linker region; the linker region probably does not contribute to the binding specificity. Required for cell homeostasis. May be involved in transcriptional regulation (Probable).

References:

[1]. Romain Villot, et al. ZNF768 links oncogenic RAS to cellular senescence. Nat Commun. 2021 Aug 17;12(1):4841. [Content Brief]

[2]. Michaela Rohrmoser, et al. MIR sequences recruit zinc finger protein ZNF768 to expressed genes. Nucleic Acids Res. 2019 Jan 25;47(2):700-715. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Name
Email *

	Sorry, but the email address you supplied was invalid.