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  5. Bletilla striata (Thunb. ex Murray) Rchb. f.
  6. Bletimalate D

Bletimalate D is a 2-isobutylmalate found in the tubers of Bletilla striata. Bletimalate D shows no significant anti-pulmonary fibrosis activity and has cytotoxicity.

For research use only. We do not sell to patients.

Bletimalate D

Bletimalate D Chemical Structure

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Bletimalate D Related Antibodies

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Description

Bletimalate D is a 2-isobutylmalate found in the tubers of Bletilla striata. Bletimalate D shows no significant anti-pulmonary fibrosis activity and has cytotoxicity[1].

In Vitro

Bletimalate D (Compound 2) (20 μM; 24 h) exhibits cytotoxicity against NIH/3T3 cells, reducing viability to 70.45 ± 6.98%[1].
Bletimalate D does not inhibit total collagen production in TGF-β1-activated NIH/3T3 cells, with an IC50 value >50 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bletimalate D Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: NIH/3T3 fibroblasts
Concentration: 20 μM
Incubation Time: 24 h
Result: Reduced cell viability to 70.45 ± 6.98%.
Molecular Weight

930.90

Formula

C42H58O23
SMILES

O[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O)OC2=CC=C(C=C2)COC([C@@](CC(C)C)(CC(OCC3=CC=C(C=C3)O[C@@H]4O[C@@H]([C@H](C([C@H]4O)O)O)CO)=O)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)OC(C)=O)CO)=O)CO
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Bletimalate D Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bletimalate DOtherscollagenNIH/3T3 cellsTGF-β1Bletilla striatapulmonary fibrosisInhibitorinhibitorinhibit

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