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  3. Bromodomain inhibitor-8

Bromodomain inhibitor-8 

Cat. No.: HY-128703 Purity: 98.02%
Handling Instructions

Bromodomain inhibitor-8 (Intermediate 21) is a BET bromodomain inhibitor for treating autoimmune and inflammatory diseases.

For research use only. We do not sell to patients.

Bromodomain inhibitor-8 Chemical Structure

Bromodomain inhibitor-8 Chemical Structure

CAS No. : 1300031-70-2

Size Price Stock Quantity
10 mM * 1 mL in Ethanol USD 385 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 550 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2650 Get quote
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Bromodomain inhibitor-8 (Intermediate 21) is a BET bromodomain inhibitor for treating autoimmune and inflammatory diseases[1].

IC50 & Target[1]

Brd

 

Molecular Weight

448.94

Formula

C₂₆H₂₅ClN₂O₃

CAS No.

1300031-70-2

SMILES

O=C(OC)C1=CC=C(C2=CC3=C(N(C(C)=O)[[email protected]@H](C)C[[email protected]]3NC4=CC=C(Cl)C=C4)C=C2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (222.75 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2275 mL 11.1373 mL 22.2747 mL
5 mM 0.4455 mL 2.2275 mL 4.4549 mL
10 mM 0.2227 mL 1.1137 mL 2.2275 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 5 mg/mL (11.14 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 5 mg/mL (11.14 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Bromodomain inhibitor-8
Cat. No.:
HY-128703
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