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Cat. No.: HY-104052

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MK-8718

MK-8718 is a potent and orally active HIV protease inhibitor containing a morpholine aspartate binding group. MK-8718 can be used for the research of infection.

For research use only. We do not sell to patients.

CAS No.: 1582729-24-5
Formula: C₃₀H₃₀ClF₆N₅O₄
Molecular Weight:674.03

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

MK-8718 Chemical Structure

CAS No.: 1582729-24-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

MK-8718 is a potent and orally active HIV protease inhibitor containing a morpholine aspartate binding group. MK-8718 can be used for the research of infection^[1].

Chemical Information

CAS No. 1582729-24-5
Molecular Weight 674.03
Formula C₃₀H₃₀ClF₆N₅O₄
SMILES

O=C(OC[C@H]1NC[C@@H](CCC2=C(NC([C@@H](N)[C@@H](C3=CC=C(Cl)C=C3)C4=CC(F)=CC(F)=C4)=O)C=NC=C2F)OC1)NCC(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bungard CJ, et al. Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group. ACS Med Chem Lett. 2016 May 9;7(7):702-7. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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