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Cat. No.: HY-111849

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Imatinib carbaldehyde

(Synonyms: CGP-57148B carbaldehyde; STI571 carbaldehyde; PROTAC ABL binding moiety 1)

Imatinib carbaldehyde (CGP-57148B carbaldehyde), the Imatinib (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER.

For research use only. We do not sell to patients.

CAS No.: 1436868-85-7
Formula: C₂₉H₂₉N₇O₂
Molecular Weight:507.59

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Imatinib carbaldehyde Chemical Structure

CAS No.: 1436868-85-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Imatinib carbaldehyde (CGP-57148B carbaldehyde), the Imatinib (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER^[1].

Chemical Information

CAS No. 1436868-85-7
Molecular Weight 507.59
Formula C₂₉H₂₉N₇O₂
SMILES

CC1=CC=C(NC(C2=CC=C(CN3CCN(C=O)CC3)C=C2)=O)C=C1NC4=NC=CC(C5=CC=CN=C5)=N4
Synonyms

CGP-57148B carbaldehyde; STI571 carbaldehyde; PROTAC ABL binding moiety 1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Imatinib carbaldehyde

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Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Imatinib carbaldehyde Related Classifications

HY-111849 Related Classifications