AXSP0056BS
AXSP0056BS is an allosteric GTP cyclohydrolase I (GCH1) inhibitor with an IC50 of 4 μM. AXSP0056BS is applicable to the research of neuropathic and inflammatory pain disorders.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
The AXSP0056BS was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
- Formule: C5H4N4O2S
- Masse moléculaire:184.18
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
AXSP0056BS (1 mM; 2-10 days) binds to the allosteric pocket of GCH1, induces quaternary structure compaction and increased flexibility of the loop adjacent to the active site, thereby converting the enzyme into an inhibitory conformation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 184.18
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Formule C5H4N4O2S
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SMILES
O=C(N1)SC2=C1C(NC(N)=N2)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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