Cortisol-selective aptamer
Cortisol-selective aptamer is a nucleic acid that selectively binds to cortisol. Cortisol-selective aptamer undergoes conformational transition upon binding to cortisol, inducing fluorescence quenching of quantum dots. Cortisol-selective aptamer can be integrated into gold nanoparticle colorimetric assays in buffer solutions to distinguish cortisol from other biomarkers of stress and liver dysfunction.
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Description
In Vitro
Cortisol-selective aptamer-conjugated red QD@MNP nanosensors enable efficient detection of cortisol in 0.1×10-1 PBS buffer, with a limit of detection of approximately 1 nM[2].
Cortisol-selective aptamer-conjugated red QD@MNP nanosensors detect cortisol in 5-fold diluted spiked saliva samples, with a limit of detection <1 nM and a linear quantification range of 0.4-400 nM; they also exhibit high selectivity for cortisol over other steroid hormones in 0.1× PBS buffer[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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SMILES
[Cortisol-selective aptamer]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cortisol-selective aptamer Related Classifications
HY-188092 Related Classifications
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