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Cat. No.: HY-P11165

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DRGN-1

DRGN-1 is an antimicrobial peptide. DRGN-1 exhibits potent antimicrobial and anti-biofilm activities, inhibiting both Gram-negative and Gram-positive bacteria, with an EC₅₀ range of 0.50-4.62 μM. DRGN-1 exerts its antimicrobial effect by disrupting bacterial membrane permeability and slightly depolarizing the membrane potential. DRGN-1 inhibits the formation of biofilms of single bacterial species and mixed species of Pseudomonas aeruginosa and Staphylococcus aureus. DRGN-1 can significantly promote the healing of uninfected and mixed biofilm-infected mouse wounds. DRGN-1 can be used for the study of infections.

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CAS No.: 2173394-02-8
Formule: C₇₁H₁₃₀N₂₀O₁₇
Masse moléculaire:1535.92

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DRGN-1 Chemical Structure

CAS No.: 2173394-02-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Chemical Information

CAS No. 2173394-02-8
Masse moléculaire 1535.92
Formule C₇₁H₁₃₀N₂₀O₁₇
Sequence

Pro-Ser-Lys-Lys-Thr-Lys-Pro-Val-Lys-Pro-Lys-Lys-Val-Ala
Sequence Shortening

PSKKTKPVKPKKVA
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Chung EMC, et al. Komodo dragon-inspired synthetic peptide DRGN-1 promotes wound-healing of a mixed-biofilm infected wound. NPJ Biofilms Microbiomes. 2017 Apr 11;3:9. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Volume _(start) Volume _(start)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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