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Cat. No.: HY-119087

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JNJ-28583867

JNJ-28583867 is an orally active and selective histamine H3 receptor antagonist (K_i=10.6 nM) and serotonin transporter (SERT) inhibitor (K_i=3.7 nM). JNJ-28583867 can be used in the research of depression.

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CAS No.: 892407-39-5
Formule: C₂₄H₃₂N₂O₂S
Masse moléculaire:412.59

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

JNJ-28583867 Chemical Structure

CAS No.: 892407-39-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
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Activité biologique

Description

IC₅₀ & Target

^[1]

H₃ receptor

10.6 nM (Ki)

Voir tous les produits spécifiques à Isoform Histamine Receptor :

Chemical Information

CAS No. 892407-39-5
Masse moléculaire 412.59
Formule C₂₄H₃₂N₂O₂S
SMILES

CSC1=CC=C([C@@H]2CN(C)CC3=C2C=CC(OCCCN4CCOCC4)=C3)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Barbier A J, et al. Pharmacological characterization of JNJ-28583867, a histamine H3 receptor antagonist and serotonin reuptake inhibitor[J]. European journal of pharmacology, 2007, 576(1-3): 43-54. [Content Brief]

Calculators

Calculateur de molarité

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
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JNJ-28583867

Voir tous les produits spécifiques à Isoform Histamine Receptor

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Description

IC50 & Target

Chemical Information

Pureté et documentation

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JNJ-28583867 Related Classifications

HY-119087 Related Classifications

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