KSK213
KSK213 is a 1,2,3-triazole-based Chlamydia infectivity inhibitor with high potency (EC50 ≤ 20 nM) against Chlamydia infectivity.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 1876429-73-0
- Formule: C28H25N3O2S
- Masse moléculaire:467.58
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | EC50 |
58 nM
Compound: 21a
|
Antimicrobial activity against Chlamydia trachomatis serovar D infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay
Antimicrobial activity against Chlamydia trachomatis serovar D infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay
|
[PMID: 26849778] |
| HeLa | EC50 |
59 nM
Compound: 21a
|
Antimicrobial activity against Chlamydia trachomatis serovar LGV-L2 infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay
Antimicrobial activity against Chlamydia trachomatis serovar LGV-L2 infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay
|
[PMID: 26849778] |
Chemical Information
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CAS No. 1876429-73-0
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Masse moléculaire 467.58
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Formule C28H25N3O2S
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SMILES
O=C(C1CSC2=C(C3CC3)C(CC4=C5C=CC=CC5=CC=C4)=C(N)C(N21)=O)NC6=CC=CC=C6
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Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)