Orotirelin
Orotirelin (CG 3509) is a thyrotrophin-releasing hormone (TRH) analogue. Orotirelin can be used in the study of neurological diseases.
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- CAS No.: 62305-86-6
- Formule: C16H19N7O5
- Masse moléculaire:389.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats (270-290 g) anaesthetized with Sodium Pentobarbitone (60mg/kg, i.p.)[1]
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Dosage:0.1-1.0 μg (0.5 μL each side)
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Administration:Intracerebral injection; once
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Result:Reversed the Pentobarbitone-induced sleeping time.
Chemical Information
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CAS No. 62305-86-6
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Masse moléculaire 389.37
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Formule C16H19N7O5
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SMILES
O=C([C@H]1N(CCC1)C([C@@H](NC(C(NC2=O)=CC(N2)=O)=O)CC3=CNC=N3)=O)N
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Synonyms
CG 3509
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. K C Fone, et al. Involvement of 5-HT2 receptors in the behaviours produced by intrathecal administration of selected 5-HT agonists and the TRH analogue (CG 3509) to rats. Br J Pharmacol. 1989 Mar;96(3):599-608. [Content Brief]
[2]. T Sharp, et al. Analeptic effects of centrally injected TRH and analogues of TRH in the pentobarbitone-anaesthetized rat. Neuropharmacology. 1984 Mar;23(3):339-48. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Orotirelin Related Classifications
HY-122353 Related Classifications
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