1001438-96-5
Chemical Structure
AMG-076
- CAS No.: 1001438-96-5
- Formula:C32H39F3N2O5S
- Molecular Weight:620.72
IUPAC Name: 1-(2-((4aR,11R,11aS)-11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydro-2H-pyrido[4,3-b]carbazol-2-yl)ethyl)cyclohexane-1-carboxylic acid compound with benzenesulfonic acid (1:1)
InChIKey: IBDOVKSLMMFQPJ-IUPOGUASSA-N
SMILES: O=C(O)C1(CCCCC1)CCN2CC[C@@]3(CC4=C([C@@H]([C@]3(C2)[H])C)C(C=C(C=C5)C(F)(F)F)=C5N4)[H].O=S(C6=CC=CC=C6)(O)=O
Biological Activity: AMG-076 is an orally bioavailable and selective MCHR1 antagonist. AMG-076 results in significant reduction in body weight gain in nonobese mice fed a high-fat diet and in high-fat diet-induced obese (DIO) mice[1].
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AMG-076 | AMG-076 is an orally bioavailable and selective MCHR1 antagonist. AMG-076 results in significant reduction in body weight gain in nonobese mice fed a high-fat diet and in high-fat diet-induced obese (DIO) mice. | |||||||||||||||||||||
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