1004990-28-6
1004990-28-6
Chemical Structure
PF-AKT400
Synonym(s): AKT protein kinase inhibitor
- CAS No.: 1004990-28-6
- Formula:C20H22F2N6O
- Molecular Weight:400.43
IUPAC Name: (S)-N-((3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl)methyl)-2,4-difluorobenzamide
InChIKey: MOZRQQTUYAYCQT-FQEVSTJZSA-N
SMILES: N[C@@](CC1)(CNC(C2=CC=C(F)C=C2F)=O)CN1C3=C4C(NC=C4CC)=NC=N3
Biological Activity: PF-AKT400 is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKBα (IC50=0.5 nM) than PKA (IC50=450 nM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-AKT400 | 98.0% | PF-AKT400 is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKBα (IC50=0.5 nM) than PKA (IC50=450 nM). | ||||||||||||||||||||
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Keywords
