1030759-58-0
1030759-58-0
Chemical Structure
FO-4-15
- CAS No.: 1030759-58-0
- Formula:C18H20N4O4S
- Molecular Weight:388.44
InChIKey: BIMKUWYNAWNDAH-UHFFFAOYSA-N
SMILES: O=S(N1CCN(CC2=NC(C3=CC=CO3)=NO2)CC1)(C4=CC=C(C)C=C4)=O
Biological Activity:
FO-4-15 is an mGluR1/CaMKIIα activator. FO-4-15 has a protective effect against H2O2 in human neuroblastoma (SH-SY5Y) cells. FO-4-15 can improve cognitive impairment in Alzheimer’s disease mice by activating the mGluR1/CaMKIIα pathway, and can reduce Aβ accumulation, hyperphosphorylated Tau, and synaptic damage[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
FO-4-15 | 99.45% | FO-4-15 is an mGluR1/CaMKIIα activator. FO-4-15 has a protective effect against H2O2 in human neuroblastoma (SH-SY5Y) cells. FO-4-15 can improve cognitive impairment in Alzheimer’s disease mice by activating the mGluR1/CaMKIIα pathway, and can reduce Aβ accumulation, hyperphosphorylated Tau, and synaptic damage. |
||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
