104408-38-0
104408-38-0
Chemical Structure
SC-44463
- CAS No.: 104408-38-0
- Formula:C19H29N3O5
- Molecular Weight:379.45
IUPAC Name: (R)-N4-hydroxy-2-isobutyl-N1-((S)-3-(4-methoxyphenyl)-1-(methylamino)-1-oxopropan-2-yl)succinamide
InChIKey: QYZPDCGWIJYZMN-ZBFHGGJFSA-N
SMILES: O=C([C@@H](CC(NO)=O)CC(C)C)N[C@H](C(NC)=O)CC1=CC=C(C=C1)OC
Biological Activity: SC-44463 is a synthetic collagenase inhibitor. SC-44463 can inhibit tumor cells invasion. SC-44463 can block ovulation, inhibit action of ovarian interstitial collagenase, and inhibit action of the small metalloproteinase of the rat uterus. SC-44463 can be used for the researches of cancer and endocrinology[1][2].
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SC-44463 | SC-44463 is a synthetic collagenase inhibitor. SC-44463 can inhibit tumor cells invasion. SC-44463 can block ovulation, inhibit action of ovarian interstitial collagenase, and inhibit action of the small metalloproteinase of the rat uterus. SC-44463 can be used for the researches of cancer and endocrinology. | |||||||||||||||||||||
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References
- [1]. Axelrod JH, et al. Expression of human recombinant plasminogen activators enhances invasion and experimental metastasis of H-ras-transformed NIH 3T3 cells. Mol Cell Biol. 1989 May;9(5):2133-41. [Content Brief]
- [2]. Butler TA, et al. Inhibition of ovulation in the perfused rat ovary by the synthetic collagenase inhibitor SC 44463. Biol Reprod. 1991 Jun;44(6):1183-8. [Content Brief]
