1047464-92-5
1047464-92-5
Chemical Structure
ZL-Pin01
- CAS No.: 1047464-92-5
- Formula:C14H17ClN2O3S
- Molecular Weight:328.81
IUPAC Name: 8-(2-chloroacetyl)-4-(furan-2-ylmethyl)-1-thia-4,8-diazaspiro[4.5]decan-3-one
InChIKey: JVOXTZLPLJUOKX-UHFFFAOYSA-N
SMILES: O=C1CSC2(CCN(C(CCl)=O)CC2)N1CC3=CC=CO3
Biological Activity: ZL-Pin01 is a high potent covalent Pin1 (Peptidyl-Prolyl Isomerase NIMA-Interacting-1) inhibitor. ZL-Pin01 shows potent disruption of the Pin1-substrate interaction with an IC50 of 1.33 μM[1].
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ZL-Pin01 | ZL-Pin01 is a high potent covalent Pin1 (Peptidyl-Prolyl Isomerase NIMA-Interacting-1) inhibitor. ZL-Pin01 shows potent disruption of the Pin1-substrate interaction with an IC50 of 1.33 μM. | |||||||||||||||||||||
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References
Keywords
