1047635-80-2
1047635-80-2
Chemical Structure
Uprosertib hydrochloride
Synonym(s): GSK2141795 hydrochloride
- No. CAS: 1047635-80-2
- Formula:C18H17Cl3F2N4O2
- Molecular Weight:465.71
IUPAC Name: (S)-N-(1-amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)furan-2-carboxamide hydrochloride
InChIKey: LAPFKCIDRPWAFU-PPHPATTJSA-N
SMILES: O=C(C1=CC(C2=C(Cl)C=NN2C)=C(Cl)O1)N[C@@H](CC3=CC=C(F)C(F)=C3)CN.Cl
Biological Activity: Uprosertib hydrochloride (GSK2141795 hydrochloride) is a potent and selective pan-Akt inhibitor with IC50 values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively.
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Uprosertib hydrochloride | Uprosertib hydrochloride (GSK2141795 hydrochloride) is a potent and selective pan-Akt inhibitor with IC50 values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively. | |||||||||||||||||||||
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