1049738-54-6
1049738-54-6
Chemical Structure
ERK-IN-4
- CAS No.: 1049738-54-6
- Formula:C14H17ClN2O3S
- Molecular Weight:328.81
IUPAC Name: (Z)-3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione hydrochloride
InChIKey: PQVLWVGMXJPJLG-MWMYENNMSA-N
SMILES: O=C(N(CCN)C/1=O)SC1=C/C2=CC=C(OCC)C=C2.[H]Cl
Biological Activity: ERK-IN-4 is an ERK inhibitor binds preferentially to ERK2 with a Kd of 5 μM. ERK-IN-4 specificity inhibits ERK Rsk-1 and Elk-1 phosphorylation. ERK-IN-4 has little effect on ERK protein phosphorylation by its upstream activator MEK1/2[1].
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ERK-IN-4 | 98.30% | ERK-IN-4 is an ERK inhibitor binds preferentially to ERK2 with a Kd of 5 μM. ERK-IN-4 specificity inhibits ERK Rsk-1 and Elk-1 phosphorylation. ERK-IN-4 has little effect on ERK protein phosphorylation by its upstream activator MEK1/2. | ||||||||||||||||||||
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References
Keywords
