105659-32-3
Chemical Structure
5-Bromo-2',3',5'-tri-O-acetyluridine
- CAS No.: 105659-32-3
- Formula:C15H17BrN2O9
- Molecular Weight:449.21
IUPAC Name: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate
InChIKey: OVWGEZUVGHETAU-HKUMRIAESA-N
SMILES: BrC1=CN(C(NC1=O)=O)[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]2OC(C)=O
Biological Activity: 5-Bromo-2',3',5'-tri-O-acetyluridine diacetate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5-Bromo-2',3',5'-tri-O-acetyluridine | 5-Bromo-2',3',5'-tri-O-acetyluridine diacetate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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