108-65-6
Chemical Structure
1-Methoxy-2-propyl acetate
Synonym(s): Propylene glycol monomethyl ether acetate
- CAS. Nr.: 108-65-6
- Formula:C6H12O3
- Molecular Weight:132.16
IUPAC Name: 1-methoxypropan-2-yl acetate
InChIKey: LLHKCFNBLRBOGN-UHFFFAOYSA-N
SMILES: CC(OC(C)=O)COC
Biological Activity: 1-Methoxy-2-propyl acetate is a volatile ester compound found in chocolate made from fermented cocoa beans. 1-Methoxy-2-propyl acetate serves as a hydrolysis substrate for esterases in blood, liver, lung, and nasal mucosa, and is rapidly hydrolyzed to propylene glycol monomethyl ether and acetic acid. 1-Methoxy-2-propyl acetate is proposed as a candidate urinary biomarker for dairy product intake. 1-Methoxy-2-propyl acetate can serve as a solvent and is applied in the electronic-grade semiconductor industry. 1-Methoxy-2-propyl acetate can be used in research related to nephropathy, hepatomegaly, and nasal irritation[1][2][3][4][5][6].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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1-Methoxy-2-propyl acetate | 99.97% | 1-Methoxy-2-propyl acetate is a volatile ester compound found in chocolate made from fermented cocoa beans. 1-Methoxy-2-propyl acetate serves as a hydrolysis substrate for esterases in blood, liver, lung, and nasal mucosa, and is rapidly hydrolyzed to propylene glycol monomethyl ether and acetic acid. 1-Methoxy-2-propyl acetate is proposed as a candidate urinary biomarker for dairy product intake. 1-Methoxy-2-propyl acetate can serve as a solvent and is applied in the electronic-grade semiconductor industry. 1-Methoxy-2-propyl acetate can be used in research related to nephropathy, hepatomegaly, and nasal irritation. | ||||||||||||||||||||
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References
- [1]. Hussain A, et al. Process design alternatives for producing ultra-high-purity electronic-grade propylene glycol monomethyl ether acetate[J]. Industrial & Engineering Chemistry Research, 2019, 58(6): 2246-2257.
- [2]. Llano S, et al. Exploring the Impact of Fermentation Time and Climate on Quality of Cocoa Bean-Derived Chocolate: Sensorial Profile and Volatilome Analysis. Foods (Basel, Switzerland). 2024 Aug 20;13(16):2614.
- [3]. Fuchsmann P, et al. Nutrivolatilomics of Urinary and Plasma Samples to Identify Candidate Biomarkers after Cheese, Milk, and Soy-Based Drink Intake in Healthy Humans. Journal of proteome research. 2020 Oct 02;19(10):4019-4033.
- [4]. Miller RR, et al. Propylene glycol monomethyl ether acetate (PGMEA) metabolism, disposition, and short-term vapor inhalation toxicity studies. Toxicology and applied pharmacology. 1984 Sep 30;75(3):521-30.
- [5]. Corley RA, et al. Development of a physiologically based pharmacokinetic model for propylene glycol monomethyl ether and its acetate in rats and humans. Toxicology letters. 2005 Mar 28;156(1):193-213.
