108351-49-1
Chemical Structure
Rodaplutin
Synonym(s): Sch 36605
- CAS No.: 108351-49-1
- Formula:C24H39N9O7
- Molecular Weight:565.62
IUPAC Name: 3-(3-(2-amino-4-methylpentanamido)-5-(1-methylguanidino)pentanamido)-6-(4-amino-5-(hydroxymethyl)-2-oxopyrimidin-1(2H)-yl)-3,6-dihydro-2H-pyran-2-carboxylic acid
InChIKey: MGPVTRZZQCEQDF-UHFFFAOYSA-N
SMILES: O=C1N(C2C=CC(NC(CC(CCN(C)C(N)=N)NC(C(CC(C)C)N)=O)=O)C(C(O)=O)O2)C=C(CO)C(N)=N1
Biological Activity: Rodaplutin (Sch 36605) is a ribosomal peptide antibiotic. Rodaplutin demonstrates anti-inflammatory effects by suppressing inflammatory mediator release in animal models. Rodaplutin is promising for research of infections and inflammatory diseases[1][2].
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Rodaplutin | Rodaplutin (Sch 36605) is a ribosomal peptide antibiotic. Rodaplutin demonstrates anti-inflammatory effects by suppressing inflammatory mediator release in animal models. Rodaplutin is promising for research of infections and inflammatory diseases. | |||||||||||||||||||||
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References
- [1]. Dellweg H, et al. Rodaplutin, a new peptidylnucleoside from Nocardioides albus. J Antibiot (Tokyo). 1988 Aug;41(8):1145-7. [Content Brief]
- [2]. Gullo V, et al. Sch 36605, a novel anti-inflammatory compound. Taxonomy, fermentation, isolation and biological properties. J Antibiot (Tokyo). 1988 Jan;41(1):20-4. [Content Brief]
