109785-20-8
Chemical Structure
Lactosyl-C18-sphingosine
Synonym(s): C18 Lactosyl(β) Ceramide; Lactosyl Sphingosine; Lyso-Lactosylceramide (synthetic)
- CAS No.: 109785-20-8
- Formula:C30H57NO12
- Molecular Weight:623.77
IUPAC Name: (2S,3R,4S,5R,6R)-2-(((2R,3S,4R,5R,6R)-6-(((2S,3R,E)-2-amino-3-hydroxyoctadec-4-en-1-yl)oxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChIKey: MQKSCOKUMZMISB-GPWKTZPCSA-N
SMILES: OC[C@@H](O[C@H]([C@@H]([C@H]1O)O)OC[C@H](N)[C@H](O)/C=C/CCCCCCCCCCCCC)[C@H]1O[C@@H]2O[C@@H]([C@@H]([C@@H]([C@H]2O)O)O)CO
Biological Activity: Lactosyl-C18-sphingosine (C18 Lactosyl(β) Ceramide; Lactosyl Sphingosine) is a bioactive sphingolipid that is a form of lactosylceramide but lacks the fatty acyl group. Lysolactosylceramide (1-50 μM) reduces the viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosyl-C18-sphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosyl-C18-sphingosine is a lysoganglioside GM3.
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Lactosyl-C18-sphingosine | Lactosyl-C18-sphingosine (C18 Lactosyl(β) Ceramide; Lactosyl Sphingosine) is a bioactive sphingolipid that is a form of lactosylceramide but lacks the fatty acyl group. Lysolactosylceramide (1-50 μM) reduces the viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosyl-C18-sphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosyl-C18-sphingosine is a lysoganglioside GM3. | |||||||||||||||||||||
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Lactosyl-C18-sphingosine-d7 | Lactosyl-C18-sphingosine-d7 is deuterium labeled Lactosyl-C18-sphingosine. | |||||||||||||||||||||
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