111174-43-7
111174-43-7
Chemical Structure
Polymyxin deacylase
Synonym(s): Polymyxin acylase
- CAS No.: 111174-43-7
- Formula:N/A
- Molecular Weight:N/A
SMILES: [Polymyxin deacylase]
Biological Activity: Polymyxin deacylase (Polymyxin acylase) is an N-myristoyl lyase. Polymyxin deacylase can deacylate polymyxin antibiotics and long-chain fatty acyl groups of proteins and peptides. Polymyxin deacylase exhibits antitumor activity against oral epithelial cancer cells. Polymyxin deacylase can be used in research on oral epithelial cancer and other cancers[1][2].
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Polymyxin deacylase | Polymyxin deacylase (Polymyxin acylase) is an N-myristoyl lyase. Polymyxin deacylase can deacylate polymyxin antibiotics and long-chain fatty acyl groups of proteins and peptides. Polymyxin deacylase exhibits antitumor activity against oral epithelial cancer cells. Polymyxin deacylase can be used in research on oral epithelial cancer and other cancers. | |||||||||||||||||||||
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References
- [1]. Yasuda N, et al. In vitro antitumor activity of polymyxin acylase from Pseudomonas sp. M-6-3. Biol Pharm Bull. 1995 Apr;18(4):615-7. [Content Brief]
- [2]. Misumi S, et al. Determination of N-myristoyl peptide sequence both by MALDI TOF MASS and with an N-myristoyl cleaving enzyme (polymyxin acylase). Biochem Biophys Res Commun. 1995 Dec 14;217(2):632-9. [Content Brief]
Keywords
