1118765-14-2
1118765-14-2
Chemical Structure
O-Desmethyl apixaban sulfate
- CAS No.: 1118765-14-2
- Formula:C24H23N5O7S
- Molecular Weight:525.54
IUPAC Name: 4-(3-carbamoyl-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-1-yl)phenyl hydrogen sulfate
InChIKey: HRIFVOGTDGFZKP-UHFFFAOYSA-N
SMILES: O=C(N)C1=NN(C2=CC=C(OS(=O)(=O)O)C=C2)C=3C(=O)N(C4=CC=C(C=C4)N5C(=O)CCCC5)CCC13
Biological Activity: O-Desmethyl apixaban sulfate is the major circulating metabolite of Apixaban (HY-50667) in humans. O-Desmethyl apixaban sulfate exhibits no inhibitory activity against human activated factor X (FXa), with a Ki > 20 μM[1].
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O-Desmethyl apixaban sulfate | O-Desmethyl apixaban sulfate is the major circulating metabolite of Apixaban (HY-50667) in humans. O-Desmethyl apixaban sulfate exhibits no inhibitory activity against human activated factor X (FXa), with a Ki > 20 μM. | |||||||||||||||||||||
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References
Keywords
