1119200-33-7
1119200-33-7
Chemical Structure
hCAIX/XII-IN-4
- CAS No.: 1119200-33-7
- Formula:C20H16N2O5
- Molecular Weight:364.35
IUPAC Name: 7-((5-(4-methoxyphenyl)-1,2,4-oxadiazol-3-yl)methoxy)-4-methyl-2H-chromen-2-one
InChIKey: PHKWAXXKGPPHRF-UHFFFAOYSA-N
SMILES: O=C1C=C(C)C2=C(O1)C=C(OCC3=NOC(C4=CC=C(OC)C=C4)=N3)C=C2
Biological Activity: hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].
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hCAIX/XII-IN-4 | hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively. | |||||||||||||||||||||
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References
Keywords
