1. Metabolic Enzyme/Protease
  2. Carbonic Anhydrase
  3. hCAIX/XII-IN-4

hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively.

For research use only. We do not sell to patients.

hCAIX/XII-IN-4 Chemical Structure

hCAIX/XII-IN-4 Chemical Structure

CAS No. : 1119200-33-7

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Description

hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].

IC50 & Target

Ki: 4.5 nM (CAXII), 4.5 nM (CAXII), >10000 nM (CAI), and > 10000 nM (CAⅡ)[1]

Molecular Weight

364.35

Formula

C20H16N2O5

CAS No.
SMILES

O=C1C=C(C)C2=C(O1)C=C(OCC3=NOC(C4=CC=C(OC)C=C4)=N3)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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hCAIX/XII-IN-4 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
hCAIX/XII-IN-4
Cat. No.:
HY-146259
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