114798-27-5
114798-27-5
Chemical Structure
EXP-7711
- CAS No.: 114798-27-5
- Formula:C22H23ClN2O3
- Molecular Weight:398.88
IUPAC Name: 4'-((2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid
InChIKey: UUPNFNCKGJOLQE-UHFFFAOYSA-N
SMILES: CCCCC1=NC(Cl)=C(CO)N1CC2=CC=C(C3=C(C=CC=C3)C(O)=O)C=C2
Biological Activity: EXP-7711 is a non peptide angiotensin II (Ang II) AT1 receptor antagonist. EXP-7711’s affinity for wild-type AT1 receptor (Ki =180 nM) is lower than peptide antagonists, but higher than losartan (Ki = 12 nM). EXP-7711 can be used for research on cardiovascular conditions[1].
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EXP-7711 | EXP-7711 is a non peptide angiotensin II (Ang II) AT1 receptor antagonist. EXP-7711’s affinity for wild-type AT1 receptor (Ki =180 nM) is lower than peptide antagonists, but higher than losartan (Ki = 12 nM). EXP-7711 can be used for research on cardiovascular conditions. | |||||||||||||||||||||
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References
Keywords
