1158607-44-3
1158607-44-3
Chemical Structure
ML358
- CAS No.: 1158607-44-3
- Formula:C21H26Cl3NO2
- Molecular Weight:430.80
IUPAC Name: N-(3-chloro-4-((4-chlorobenzyl)oxy)-5-ethoxybenzyl)cyclopentanamine hydrochloride
InChIKey: ZAMVVVGRBNNUSR-UHFFFAOYSA-N
SMILES: CCOC1=C(C(Cl)=CC(CNC2CCCC2)=C1)OCC3=CC=C(C=C3)Cl.[H]Cl
Biological Activity: ML358 is a first in class, potent, and selective inhibitor of the SKN-1 pathway (IC50=0.24 μM). ML358 sensitizes the model nematode C. elegans to oxidants and anthelmintic. ML358 potentially used as adjuvants to increase the efficacy and useful life of current anthelmintics[1].
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ML358 | ML358 is a first in class, potent, and selective inhibitor of the SKN-1 pathway (IC50=0.24 μM). ML358 sensitizes the model nematode C. elegans to oxidants and anthelmintic. ML358 potentially used as adjuvants to increase the efficacy and useful life of current anthelmintics. | |||||||||||||||||||||
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References
Keywords
