116666-63-8

Mibefradil dihydrochloride Chemical Structure
116666-63-8

Chemical Structure

Mibefradil dihydrochloride

Synonym(s): Ro 40-5967 dihydrochloride

  • CAS No.: 116666-63-8
  • Formula:C29H40Cl2FN3O3
  • Molecular Weight:568.55

IUPAC Name: (1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate dihydrochloride

InChIKey: MTJLQTFHJIHXIX-GDUXWEAWSA-N

SMILES: O=C(O[C@@]1(CCN(CCCC2=NC3=CC=CC=C3N2)C)[C@@H](C(C)C)C4=C(C=C(F)C=C4)CC1)COC.[H]Cl.[H]Cl

Biological Activity: Mibefradil dihydrochloride (Ro 40-5967 dihydrochloride) is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively)[1].

Cat. No. Product Name Purity Description Pricing
HY-15553A
Mibefradil dihydrochloride 99.71% Mibefradil dihydrochloride (Ro 40-5967 dihydrochloride) is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively).
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References