1169694-98-7
1169694-98-7
Chemical Structure
CDK4/6-IN-16
- CAS No.: 1169694-98-7
- Formula:C27H33FN8O
- Molecular Weight:504.60
IUPAC Name: 2-((1-(6-((9-cyclopentyl-8-fluoro-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperidin-4-yl)(methyl)amino)ethan-1-ol
InChIKey: MNCSFNFCKABAFF-UHFFFAOYSA-N
SMILES: FC1=NC=CC2=C1N(C3CCCC3)C4=C2C=NC(NC5=NC=C(N6CCC(CC6)N(CCO)C)C=C5)=N4
Biological Activity: CDK4/6-IN-16 (example 195) is a potent CDK4 and CDK6 inhibitor, with an IC50 of 0.013 μM for CDK4. CDK4/6-IN-16 can be used for the research of CDK4-mediated disorders, such as cancer[1].
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CDK4/6-IN-16 | CDK4/6-IN-16 (example 195) is a potent CDK4 and CDK6 inhibitor, with an IC50 of 0.013 μM for CDK4. CDK4/6-IN-16 can be used for the research of CDK4-mediated disorders, such as cancer. | |||||||||||||||||||||
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References
Keywords
