1175526-27-8
1175526-27-8
Chemical Structure
AM211
Synonym(s): AM211 free acid
- CAS No.: 1175526-27-8
- Formula:C27H27F3N2O4
- Molecular Weight:500.51
IUPAC Name: 2-(2'-((3-benzyl-1-ethylureido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetic acid
InChIKey: OPXIRFWNLBDKQB-UHFFFAOYSA-N
SMILES: O=C(O)CC1=CC(C2=CC=C(C(F)(F)F)C=C2CN(CC)C(NCC3=CC=CC=C3)=O)=C(OC)C=C1
Biological Activity: AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AM211 | 98.79% | AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively. | ||||||||||||||||||||
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