1182215-65-1
1182215-65-1
Chemical Structure
Glembatumumab vedotin
Synonym(s): CDX-011; CR011-vcMMAE
- CAS No.: 1182215-65-1
- Formula:N/A
- Molecular Weight:150000 (average)
SMILES: [Glembatumumab vedotin]
Biological Activity: Glembatumumab vedotin (CDX-011) is an ADC comprising a fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB) and conjugated to the potent tubulinbinding cytotoxic agent MMAE via a protease-sensitive vc linker. Glembatumumab vedotin has potent anticancer effects[1].
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Glembatumumab vedotin | ≥99.0% | Glembatumumab vedotin (CDX-011) is an ADC comprising a fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB) and conjugated to the potent tubulinbinding cytotoxic agent MMAE via a protease-sensitive vc linker. Glembatumumab vedotin has potent anticancer effects. | ||||||||||||||||||||
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References
Keywords
