119-67-5
Chemical Structure
2-Carboxybenzaldehyde
Synonym(s): Phthalaldehydic acid
- CAS No.: 119-67-5
- Formula:C8H6O3
- Molecular Weight:150.13
IUPAC Name: 2-formylbenzoic acid
InChIKey: DYNFCHNNOHNJFG-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=CC=C1C=O
Biological Activity: 2-Carboxybenzaldehyde (Phthalaldehydic acid) is a key intermediate metabolite in the biodegradation process of polycyclic aromatic hydrocarbons, and also a specific substrate for CBA reductase and NAD-dependent 2-carboxybenzaldehyde dehydrogenase. 2-Carboxybenzaldehyde undergoes regioselective reduction via CBA reductase in mammalian tissues to produce 2-hydroxymethylbenzoic acid. 2-Carboxybenzaldehyde is converted to phthalic acid by NAD-dependent dehydrogenase during bacterial degradation. 2-Carboxybenzaldehyde can be used in relevant research in fields such as organic synthesis[1][2][3].
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2-Carboxybenzaldehyde | 99.94% | 2-Carboxybenzaldehyde (Phthalaldehydic acid) is a key intermediate metabolite in the biodegradation process of polycyclic aromatic hydrocarbons, and also a specific substrate for CBA reductase and NAD-dependent 2-carboxybenzaldehyde dehydrogenase. 2-Carboxybenzaldehyde undergoes regioselective reduction via CBA reductase in mammalian tissues to produce 2-hydroxymethylbenzoic acid. 2-Carboxybenzaldehyde is converted to phthalic acid by NAD-dependent dehydrogenase during bacterial degradation. 2-Carboxybenzaldehyde can be used in relevant research in fields such as organic synthesis. | ||||||||||||||||||||
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2-Carboxybenzaldehyde (Standard) | ≥98% | 2-Carboxybenzaldehyde (Standard) (Phthalaldehydic acid (Standard)) is the analytical standard of 2-Carboxybenzaldehyde (HY-Y1771). This product is intended for research and analytical applications. 2-Carboxybenzaldehyde (Phthalaldehydic acid) is a key intermediate metabolite in the biodegradation process of polycyclic aromatic hydrocarbons, and also a specific substrate for CBA reductase and NAD-dependent 2-carboxybenzaldehyde dehydrogenase. 2-Carboxybenzaldehyde undergoes regioselective reduction via CBA reductase in mammalian tissues to produce 2-hydroxymethylbenzoic acid. 2-Carboxybenzaldehyde is converted to phthalic acid by NAD-dependent dehydrogenase during bacterial degradation. 2-Carboxybenzaldehyde can be used in relevant research in fields such as organic synthesis. | ||||||||||||||||||||
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References
- [1]. Tonda K, et al. Purification and molecular properties of 2-carboxybenzaldehyde (CBA) reductase from phenobarbital-treated rat liver. Xenobiotica; the fate of foreign compounds in biological systems. 1992 Jun;22(6):691-9. [Content Brief]
- [2]. Kiyohara H, et al. Isolation and some properties of NAD-linked 2-carboxybenzaldehyde dehydrogenase in Alcaligenes faecalis AFK 2 grown on phenanthrene. J Gen Appl Microbiol. 1981;27:443-455.
- [3]. Tai XS, et al. A Ca(II) Coordination Polymer of 2-Carboxybenzaldehyde: Synthesis, Crystal Structure, and Catalytic Activity in Oxidation of Benzyl Alcohol. Crystals. 2018;8(4):150.
