1196119-03-5
1196119-03-5
Chemical Structure
NCL1
- CAS No.: 1196119-03-5
- Formula:C27H29N3O3
- Molecular Weight:443.54
IUPAC Name: N-((2S)-4-(3-(2-aminocyclopropyl)phenoxy)-1-(benzylamino)-1-oxobutan-2-yl)benzamide
InChIKey: DTPSXFMGMQOVTG-STEQJIOHSA-N
SMILES: O=C(N[C@H](C(NCC1=CC=CC=C1)=O)CCOC2=CC=CC(C3C(N)C3)=C2)C4=CC=CC=C4
Biological Activity: NCL1 is a phenylcyclopropylamine (PCPA)-based Lysine-specific demethylase 1 (LSD1) inhibitor. NCL1 selectively inhibits LSD1 in preference to LSD2, with IC50 values of 2.5 and 26 μM for LSD1 and LSD2, respectively[1].
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NCL1 | NCL1 is a phenylcyclopropylamine (PCPA)-based Lysine-specific demethylase 1 (LSD1) inhibitor. NCL1 selectively inhibits LSD1 in preference to LSD2, with IC50 values of 2.5 and 26 μM for LSD1 and LSD2, respectively. | |||||||||||||||||||||
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References
Keywords
