1206619-37-5
1206619-37-5
Chemical Structure
GSK2220691
- CAS No.: 1206619-37-5
- Formula:C32H33N5O3
- Molecular Weight:535.64
InChIKey: MSNUQZMCADJKQR-IBGGVINMSA-N
SMILES: O=C(N[C@@H](C(C)(C)C)C(N1[C@](C2)([H])CN(C(C3=CC=C(C4=CC=CC=C4)C=N3)=O)[C@]2([H])C1)=O)C5=CC6=C(N5)C=CC=C6
Biological Activity: SK2220691 is a potent TRPV4 inhibitor. SK2220691 inhibits pulmonary edema induced by GSK1016790. SK2220691 inhibits HCl-induced increases in key factors such as VEGF, keratinocyte-derived chemokine (KC; CXCL1), and granulocyte colony-stimulating factor (GCSF)[1].
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GSK2220691 | 99.96% | SK2220691 is a potent TRPV4 inhibitor. SK2220691 inhibits pulmonary edema induced by GSK1016790. SK2220691 inhibits HCl-induced increases in key factors such as VEGF, keratinocyte-derived chemokine (KC; CXCL1), and granulocyte colony-stimulating factor (GCSF). | ||||||||||||||||||||
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