1206695-46-6
1206695-46-6
Chemical Structure
Fesoterodine L-mandelate
- CAS 番号: 1206695-46-6
- Formula:C34H45NO6
- Molecular Weight:563.72
IUPAC Name: (R)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenyl isobutyrate (S)-2-hydroxy-2-phenylacetate
InChIKey: BUMCIEARGQDQNL-SXTNJFIWSA-N
SMILES: O[C@H](C(O)=O)C1=CC=CC=C1.O=C(C(C)C)OC2=CC=C(CO)C=C2[C@@H](C3=CC=CC=C3)CCN(C(C)C)C(C)C
Biological Activity: Fesoterodine L-mandelate is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine L-mandelate is used for the overactive bladder (OAB)[1][2].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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Fesoterodine L-mandelate | 98.92% | Fesoterodine L-mandelate is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine L-mandelate is used for the overactive bladder (OAB). | ||||||||||||||||||||
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References
- [1]. Ellsworth P, et al. Fesoterodine for the treatment of urinary incontinence and overactive bladder. Ther Clin Risk Manag. 2009;5:869-76. Epub 2009 Nov 18. [Content Brief]
- [2]. Didem Yilmaz-Oral, et al. The Beneficial Effect of Fesoterodine, a Competitive Muscarinic Receptor Antagonist on Erectile Dysfunction in Streptozotocin-induced Diabetic Rats [Content Brief]
