1212650-12-8
Chemical Structure
8-Bromo-9-(β-D-xylofuranosyl) guanine
- CAS No.: 1212650-12-8
- Formula:C10H12BrN5O5
- Molecular Weight:362.14
IUPAC Name: 2-amino-8-bromo-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one
InChIKey: ASUCSHXLTWZYBA-SAFLGMAISA-N
SMILES: O[C@@H]1[C@@H](O)[C@@H](CO)O[C@H]1N(C(Br)=N2)C3=C2C(NC(N)=N3)=O
Biological Activity: 8-Bromo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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8-Bromo-9-(β-D-xylofuranosyl) guanine | 8-Bromo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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