1216629-00-3
1216629-00-3
Chemical Structure
3-Methyl-GABA
- CAS No.: 1216629-00-3
- Formula:C20H30N2O10S2
- Molecular Weight:522.59
IUPAC Name: 4-amino-3-methylbutanoic acid compound with naphthalene-1,5-disulfonic acid (2:1)
InChIKey: XDPUYXWLPXNCDY-UHFFFAOYSA-N
SMILES: O=S(C1=C2C=CC=C(S(=O)(O)=O)C2=CC=C1)(O)=O.O=C(O)CC(C)CN.O=C(O)CC(C)CN
Biological Activity: 3-Methyl-GABA is a potent GABA aminotransferase activator. 3-Methyl-GABA can fit the binding pocket of GABAA receptor (GABAaR). 3-Methyl-GABA can activate L-glutamic acid decarboxylase (GAD). 3-Methyl-GABA has anticonvulsant activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3-Methyl-GABA | 99.86% | 3-Methyl-GABA is a potent GABA aminotransferase activator. 3-Methyl-GABA can fit the binding pocket of GABAA receptor (GABAaR). 3-Methyl-GABA can activate L-glutamic acid decarboxylase (GAD). 3-Methyl-GABA has anticonvulsant activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.71
HY-Y17251,5-Naphthalenedisulfonic acid -
Similarity Score 0.71
HY-W0090711,5-Naphthalenedisulfonic acid tetrahydrate -
Similarity Score 0.61
HY-W011232Sodium naphthalene-1,5-disulfonate -
Similarity Score 0.57
HY-D1080EDANS -
Similarity Score 0.56
HY-W0933534,8-Disulfonaphthalene-2,6-dicarboxylic acid -
Similarity Score 0.53
HY-D0142Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium -
Similarity Score 0.52
HY-10061ALesogaberan napadisylate -
Similarity Score 0.52
HY-D1079EDANS sodium -
Similarity Score 0.51
HY-D1524N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid -
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References
- [1]. R B Silverman, et al. 3-Alkyl-4-aminobutyric acids: the first class of anticonvulsant agents that activates L-glutamic acid decarboxylase. J Med Chem. 1991 Jul;34(7):2295-8. [Content Brief]
- [2]. Z. YANG, et al. MOLECULAR INTERACTIONS OF GABA ANALOGUES AGAINST THE α+β-INTERFACE OF GABAARECEPTOR: DOCKING AND MOLECULAR DYNAMICS STUDIES. Digest Journal of Nanomaterials and Biostructures, Vol. 10, No. 3, July -September 2015.
