1217448-19-5
1217448-19-5
Chemical Structure
Galnon TFA
- CAS 番号: 1217448-19-5
- Formula:C42H47F3N4O8
- Molecular Weight:792.84
IUPAC Name: (9H-fluoren-9-yl)methyl ((S)-1-(((S)-6-amino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxohexan-2-yl)amino)-3-cyclohexyl-1-oxopropan-2-yl)carbamate 2,2,2-trifluoroacetate
InChIKey: NLKOPSMADZXEPE-WDAFUDAASA-N
SMILES: OC(C(F)(F)F)=O.CC(C1=CC=C(C=C1O2)NC([C@H](CCCCN)NC([C@H](CC3CCCCC3)NC(OCC4C5=CC=CC=C5C6=CC=CC=C64)=O)=O)=O)=CC2=O
Biological Activity: Galnon TFA is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon TFA exhibits anticonvulsant and anxiolytic effects[1][2].
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Galnon TFA | 98.88% | Galnon TFA is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon TFA exhibits anticonvulsant and anxiolytic effects. | ||||||||||||||||||||
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Galnon TFA (Standard) | ≥98% | Galnon TFA (Standard) is the analytical standard of Galnon TFA (HY-103536A). This product is intended for research and analytical applications. Galnon TFA is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon TFA exhibits anticonvulsant and anxiolytic effects. | ||||||||||||||||||||
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References
- [1]. Bartfai T, et, al. Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10470-5. [Content Brief]
- [2]. Rajarao SJR, et, al. Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon. Neuropeptides. 2007 Oct;41(5):307-20. [Content Brief]
