1219407-55-2
1219407-55-2
Chemical Structure
(rac)-Nebivolol-d4
- CAS No.: 1219407-55-2
- Formula:C22H21D4F2NO4
- Molecular Weight:409.46
IUPAC Name: 2,2'-azanediylbis(1-(6-fluorochroman-2-yl)ethan-2,2-d2-1-ol)
InChIKey: KOHIRBRYDXPAMZ-AREBVXNXSA-N
SMILES: OC(C1OC2=CC=C(F)C=C2CC1)C([2H])([2H])NC([2H])([2H])C(C3OC4=CC=C(F)C=C4CC3)O
Biological Activity: (rac)-Nebivolol-d4 is a labelled racemic Nebivolol. Nebivolol selectively inhibits β1- adrenergic receptor with IC50 of 0.8 nM[1][2].
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(rac)-Nebivolol-d4 | (rac)-Nebivolol-d4 is a labelled racemic Nebivolol. Nebivolol selectively inhibits β1- adrenergic receptor with IC50 of 0.8 nM. | |||||||||||||||||||||
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(Rac)-Nebivolol-d2,15N | (Rac)-Nebivolol-d2,15N is 15N and deuterated labeled (Rac)-Nebivolol (HY-B0203B). (Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective β1-adrenergic receptor antagonist with an IC50 value of 0.8 nM. Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation in the early stages of ethanol-induced cardiac toxicity. Vasodilatory activity. | |||||||||||||||||||||
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(Rac)-Nebivolol | (Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective β1-adrenergic receptor antagonist with an IC50 value of 0.8 nM. Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation in the early stages of ethanol-induced cardiac toxicity. Vasodilatory activity. | |||||||||||||||||||||
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