1219531-58-4
1219531-58-4
Chemical Structure
Anagrelide-13C3
Synonym(s): BL 4162A-13C3; BMY 26538-01-13C3
- CAS No.: 1219531-58-4
- Formula:C713C3H7Cl2N3O
- Molecular Weight:259.07
InChIKey: OTBXOEAOVRKTNQ-PTCNTQLJSA-N
SMILES: ClC1=C(C=CC2=C1CN3[13C]([H])([13C](N[13C]3=N2)=O)[H])Cl
Biological Activity: Anagrelide-13C3 (BL 4162A-13C3) is 13C labeled Anagrelide[1].
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Anagrelide-13C3 | Anagrelide-13C3 (BL 4162A-13C3) is 13C labeled Anagrelide. | |||||||||||||||||||||
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Anagrelide-13C2,15N,d2 | Anagrelide-13C2,15N,d2 is 15N and deuterated labeled Anagrelide (HY-B0523). Anagrelide is a potent inhibitor of phosphodiesterase type III (PDE3) (IC50=36 nM). Anagrelide, an imidazoquinazoline derivative, acts as an inhibitor of platelet aggregation. Anagrelide inhibits bone marrow megakaryocytopoiesis. Anagrelide decreases gastrointestinal stromal tumor (GIST) cell proliferation and promotes their apoptosis in vitro. Anagrelide is a platelet-lowering agent and plays in the antithrombopoietic action. | |||||||||||||||||||||
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Anagrelide | 99.87% | Anagrelide is a potent inhibitor of phosphodiesterase type III (PDE3) (IC50=36 nM). Anagrelide, an imidazoquinazoline derivative, acts as an inhibitor of platelet aggregation. Anagrelide inhibits bone marrow megakaryocytopoiesis. Anagrelide decreases gastrointestinal stromal tumor (GIST) cell proliferation and promotes their apoptosis in vitro. Anagrelide is a platelet-lowering agent and plays in the antithrombopoietic action. | ||||||||||||||||||||
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References
