123997-26-2
Chemical Structure
Eprinomectin
Synonym(s): MK-397
- CAS No.: 123997-26-2
- Formula:N/A
- Molecular Weight:N/A
InChIKey: ZKWQQXZUCOBISE-AMPAAKTKSA-N
SMILES: CC(C)C.O[C@]1([C@](C=C2C)([H])C(O[C@]3([H])C[C@](O[C@H]([R])[C@H]4C)(C=C4)O[C@@](C/C=C5\C)([H])C3)=O)[C@]([C@@H]2O)([H])OC/C1=C\C=C\[C@@H]([C@@H]5O[C@H](O[C@H]6C)C[C@@H]([C@H]6O[C@H](O[C@H]7C)C[C@@H]([C@@H]7NC(C)=O)OC)OC)C.CC(C)CC.[B1a].[B1b]
Biological Activity: Eprinomectin (MK-397) is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Eprinomectin | 99.42% | Eprinomectin (MK-397) is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity. | ||||||||||||||||||||
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Eprinomectin (Standard) | ≥98% | Eprinomectin (Standard) is the analytical standard of Eprinomectin. This product is intended for research and analytical applications. Eprinomectin is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity. | ||||||||||||||||||||
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Eprinomectin-d3 | 99.2% | Eprinomectin-d3 (MK-397-d3) is the deuterium-labeled Eprinomectin (HY-12643). Eprinomectin is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity. | ||||||||||||||||||||
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References
- [1]. Samy A, et al. Eprinomectin: a derivative of ivermectin suppresses growth and metastatic phenotypes of prostate cancer cells by targeting the β-catenin signaling pathway. J Cancer Res Clin Oncol. 2023 Sep;149(11):9085-9104. [Content Brief]
- [2]. Shoop WL, et al. Eprinomectin: a novel avermectin for use as a topical endectocide for cattle. Int J Parasitol. 1996 Nov;26(11):1237-42. [Content Brief]
- [3]. do Nascimento CG, et al. Injectable eprinomectin for cattle: Tick efficacy and pharmacokinetics. J Vet Pharmacol Ther. 2020 Mar;43(2):171-178. [Content Brief]
