1269440-17-6
1269440-17-6
Chemical Structure
Encorafenib
Synonym(s): LGX818
- CAS No.: 1269440-17-6
- Formula:C22H27ClFN7O4S
- Molecular Weight:540.01
IUPAC Name: methyl (S)-(1-((4-(3-(5-chloro-2-fluoro-3-(methylsulfonamido)phenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propan-2-yl)carbamate
InChIKey: CMJCXYNUCSMDBY-ZDUSSCGKSA-N
SMILES: O=C(OC)N[C@@H](C)CNC1=NC=CC(C2=CN(C(C)C)N=C2C3=CC(Cl)=CC(NS(=O)(C)=O)=C3F)=N1
Biological Activity: Encorafenib (LGX818) is a highly potent BRAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing BRAFV600E (EC50=4 nM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Encorafenib | 99.94% | Encorafenib (LGX818) is a highly potent BRAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing BRAFV600E (EC50=4 nM). | ||||||||||||||||||||
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Encorafenib (Standard) | ≥98% | Encorafenib (Standard) is the analytical standard of Encorafenib. This product is intended for research and analytical applications. Encorafenib (LGX818) is a highly potent BRAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing BRAFV600E (EC50=4 nM). | ||||||||||||||||||||
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Encorafenib-13C,d3 | 98.14% | Encorafenib-13C,d3 is the 13C- and deuterium labeled Encorafenib. Encorafenib (LGX818) is a highly potent BRAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing BRAFV600E (EC50=4 nM). | ||||||||||||||||||||
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