1269662-73-8
1269662-73-8
Chemical Structure
Pyrotinib
Synonym(s): SHR-1258
- CAS No.: 1269662-73-8
- Formula:C32H31ClN6O3
- Molecular Weight:583.08
IUPAC Name: (R,E)-N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-3-(1-methylpyrrolidin-2-yl)acrylamide
InChIKey: SADXACCFNXBCFY-IYNHSRRRSA-N
SMILES: O=C(NC1=C(OCC)C=C2N=CC(C#N)=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)C2=C1)/C=C/[C@@H]5N(C)CCC5
Biological Activity: Pyrotinib (SHR-1258) is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pyrotinib | 99.89% | Pyrotinib (SHR-1258) is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively. | ||||||||||||||||||||
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Pyrotinib (Standard) | ≥98% | Pyrotinib (Standard) is the analytical standard of Pyrotinib (HY-104065). This product is intended for research and analytical applications. Pyrotinib (SHR-1258) is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively. | ||||||||||||||||||||
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References
Keywords
